Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | SELP | P16109 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16120998 | 0.90 | LMNA (0.44) | IGF2RLMNAALKBH5SUCNR1EGLN1 | |
| SCHEMBL676905 | 0.84 | SLC6A12 (0.38) | LMNAALKBH5SUCNR1EGLN1SLC6A12 | |
| SCHEMBL28655709 | 0.84 | SLC6A12 (0.38) | LMNAALKBH5SUCNR1EGLN1SLC6A12 | |
| SCHEMBL10477587 | 0.82 | SLC6A12 (0.36) | LMNAALKBH5SUCNR1EGLN1SLC6A12 | |
| SCHEMBL9410509 | 0.81 | TSHR (0.46) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL2623087 | 0.81 | CAMK2A (0.40) | IGF2RLMNAALKBH5SUCNR1EGLN1 | |
| SCHEMBL11576115 | 0.79 | FFAR3 (0.46) | SLC22A6TSHRMAPTFFAR3HDAC3 | |
| SCHEMBL28821679 | 0.79 | KAT2A (0.38) | SLC22A6TSHRMAPTFFAR3HDAC3 | |
| SCHEMBL7994854 | 0.79 | FFAR3 (0.40) | IGF2RLMNAALKBH5SUCNR1EGLN1 | |
| SCHEMBL1252905 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014150384-A1 | METHOD OF MANUFACTURE OF OCTANEDIOIC ACID, PRECURSORS, AND DERIVATIVES | SEGETIS, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| EP-2429587-A1 | ORGANISMS FOR THE PRODUCTION OF CYCLOHEXANONE | Genomatica, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132845-A1 | ORGANISMS FOR THE PRODUCTION OF CYCLOHEXANONE | GENOMATICA, INC. (US) | 2010-11-18 | — | — | WO | disclosed |