SCHEMBL676905

SCHEMBL676905

O=C(O)CC1OC1CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A12 P48065 5/20 0.38
SLC6A11 P48066 5/20 0.38
SLC6A13 Q9NSD5 5/20 0.38
SUCNR1 Q9BXA5 2/20 0.35
HSD11B1 P28845 1/20 0.35
LDHA P00338 1/20 0.33
SRR Q9GZT4 1/20 0.33
LMNA P02545 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
ITGB3 P05106 1/20 0.33
ITGB2 P05107 1/20 0.33
ITGB1 P05556 1/20 0.33
ITGAV P06756 1/20 0.33
ITGA2B P08514 1/20 0.33
ITGA5 P08648 1/20 0.33
ITGB5 P18084 1/20 0.33
ITGAL P20701 1/20 0.33
APEX1 P27695 1/20 0.32
SLC6A1 P30531 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28655709 1.00 SLC6A12 (0.38) SLC6A12SLC6A11SLC6A13SUCNR1HSD11B1
SCHEMBL10477587 0.97 SLC6A12 (0.36) SLC6A12SLC6A11SLC6A13SUCNR1HSD11B1
SCHEMBL11698166 0.89
SCHEMBL5413833 0.87
SCHEMBL3062281 0.87
SCHEMBL5413831 0.87
SCHEMBL747060 0.84 IGF2R (0.39) SLC6A12SLC6A11SLC6A13SUCNR1LMNA
SCHEMBL28821679 0.83 KAT2A (0.38) TSHRFFAR3OR51E2
SCHEMBL3259081 0.81 MAPT (0.33)
SCHEMBL1252905 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102796261-A Polyamine derivative, as well as preparation method and application thereof GUANGZHOU XINGYE TECHNOLOGY CO LTD 2012-11-28 CN claimed
CN-102796627-A Washing composition GUANGZHOU STARTEC SCIENCE & TECHNOLOGY CO LTD 2012-11-28 CN claimed
US-20090274741-A1 POLYMERS CONTAINING POLY(ESTER AMIDES) AND AGENTS FOR USE WITH MEDICAL ARTICLES AND METHODS OF FABRICATING THE SAME ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2009-11-05 US claimed
JP-2008500430-A 2008-01-10 JP claimed
EP-1828281-A2 POLYMERS CONTAINING POLY(ESTER AMIDES) AND AGENTS FOR USE WITH MEDICAL ARTICLES AND METHODS OF FABRICATING THE SAME ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2007-09-05 EP claimed
WO-2005118681-A2 POLYMERS CONTAINING POLY(ESTER AMIDES) AND AGENTS FOR USE WITH MEDICAL ARTICLES AND METHODS OF FABRICATING THE SAME ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2005-12-15 WO claimed
US-20050265960-A1 Polymers containing poly(ester amides) and agents for use with medical articles and methods of fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2005-12-01 US claimed
US-5147791-A Reacting diester and dialcohol in presence of enzyme catalyst;enantiomorphs UNIVERSITY OF NEW MEXICO (US) 1992-09-15 US claimed
JP-54043297-A None JP disclosed
US-9603943-B2 Polyesteramide platform for site specific drug delivery ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2017-03-28 US disclosed
US-20150290336-A1 POLYESTERAMIDE PLATFORM FOR SITE SPECIFIC DRUG DELIVERY ABBOTT CARDIOVASCULAR SYSTEMS (US) 2015-10-15 US disclosed
US-9095619-B2 Polyesteramide platform for site specific drug delivery ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2015-08-04 US disclosed
US-20150010491-A1 POLYESTERAMIDE PLATFORM FOR SITE SPECIFIC DRUG DELIVERY ABBOTT CARDIOVASCULAR SYSTEMS (US) 2015-01-08 US disclosed
US-8865148-B2 Polyesteramide platform for site specific drug delivery ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2014-10-21 US disclosed
US-20060111546-A1 Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2006-05-25 US disclosed
US-20050288481-A1 Design of poly(ester amides) for the control of agent-release from polymeric compositions ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2005-12-29 US disclosed
WO-2005118681-A2 POLYMERS CONTAINING POLY(ESTER AMIDES) AND AGENTS FOR USE WITH MEDICAL ARTICLES AND METHODS OF FABRICATING THE SAME ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2005-12-15 WO disclosed
US-20050265960-A1 Polymers containing poly(ester amides) and agents for use with medical articles and methods of fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2005-12-01 US disclosed
CN-1454930-A Polyester composition EASTMAN CHEM CO (US) 2003-11-12 CN disclosed
JP-S5443297-A PROCUCTION OF EPOXY GROUP-CONTAINING POLYAMIDE JAPAN SYNTHETIC RUBBER CO LTD 1979-04-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150010491-A1 POLYESTERAMIDE PLATFORM FOR SITE SPECIFIC DRUG DELIVERY CES2, KIT, NAAA SLC6A12 1877/4885SLC6A11 1770/4885SLC6A13 1922/4885
US-20090274741-A1 POLYMERS CONTAINING POLY(ESTER AMIDES) AND AGENTS FOR USE WITH MEDICAL ARTICLES AND METHODS OF FABRICATING THE SAME BCAT2, PAM, BCAT1 SLC6A12 1684/4885SLC6A11 1125/4885SLC6A13 909/4885
US-20050265960-A1 Polymers containing poly(ester amides) and agents for use with medical articles and methods of fabricating the same BCAT2, PAM, BCAT1 SLC6A12 1684/4885SLC6A11 1125/4885SLC6A13 909/4885
US-20150290336-A1 POLYESTERAMIDE PLATFORM FOR SITE SPECIFIC DRUG DELIVERY CES2, KIT, NAAA SLC6A12 1877/4885SLC6A11 1770/4885SLC6A13 1922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.