Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472518 | 0.91 | LMNA (0.45) | LMNAP2RY12ADRB3ADRB2ADRB1 | |
| SCHEMBL7560376 | 0.89 | LMNA (0.56) | LMNAP2RY12ADRB3ADRB2ADRB1 | |
| SCHEMBL7461831 | 0.88 | LMNA (0.46) | LMNAP2RY12ADRB3ADRB2ADRB1 | |
| SCHEMBL7467963 | 0.87 | LMNA (0.44) | LMNAABCB11P2RY12ADRB3ADRB2 | |
| SCHEMBL7467859 | 0.87 | LMNA (0.45) | LMNAP2RY12ADRB3ADRB2ADRB1 | |
| SCHEMBL7470654 | 0.85 | P2RY12 (0.47) | LMNAABCB11P2RY12ADRB3ADRB2 | |
| SCHEMBL7473044 | 0.82 | ADRB3 (0.52) | LMNAP2RY12ADRB3ADRB2ADRB1 | |
| SCHEMBL7469004 | 0.82 | ADRB3 (0.52) | LMNAP2RY12ADRB3ADRB2ADRB1 | |
| SCHEMBL5203047 | 0.81 | ADRB3 (0.48) | LMNAADRB3ADRB2ADRB1MAPT | |
| SCHEMBL6140089 | 0.81 | P2RY12 (0.41) | LMNAP2RY12MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-B1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI SYNTHELABO (FR) | 2002-08-14 | — | — | EP | disclosed |