Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 10/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469004 | 1.00 | ADRB3 (0.52) | ADRB3ADRB1ADRB2HRH3LMNA | |
| SCHEMBL7560376 | 0.91 | LMNA (0.56) | ADRB3ADRB1ADRB2HRH3LMNA | |
| SCHEMBL6301392 | 0.89 | HRH3 (0.47) | ADRB3ADRB1ADRB2HRH3LMNA | |
| SCHEMBL7469574 | 0.89 | HRH3 (0.49) | ADRB3ADRB1ADRB2HRH3LMNA | |
| SCHEMBL5202580 | 0.88 | ADRB3 (0.55) | ADRB3ADRB1ADRB2LMNAMAPT | |
| SCHEMBL7469677 | 0.88 | ADRB1 (0.46) | ADRB3ADRB1ADRB2HRH3LMNA | |
| SCHEMBL6944610 | 0.87 | ADRB3 (0.53) | ADRB3ADRB1ADRB2HRH3LMNA | |
| SCHEMBL6953322 | 0.87 | HRH3 (0.44) | ADRB3ADRB1ADRB2HRH3LMNA | |
| SCHEMBL7461019 | 0.87 | PIK3CA (0.52) | ADRB3ADRB1ADRB2LMNAMAPT | |
| SCHEMBL7467963 | 0.86 | LMNA (0.44) | ADRB3ADRB1ADRB2HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-B1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI SYNTHELABO (FR) | 2002-08-14 | — | — | EP | disclosed |
| EP-1087961-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065895-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 1999-12-23 | — | — | WO | disclosed |