Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467833 | 0.89 | PRKD3 (0.48) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7052910 | 0.87 | PRKD3 (0.47) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7468709 | 0.84 | PRKD3 (0.45) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7051582 | 0.81 | DPP4 (0.56) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7468160 | 0.81 | DPP4 (0.56) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7470666 | 0.79 | OPRK1 (0.49) | MAPTMAPK1HTTKDM4ETSHR | |
| SCHEMBL7463261 | 0.79 | CASP3 (0.42) | MAPTMAPK1HTTKDM4ETSHR | |
| SCHEMBL30596364 | 0.75 | NOTUM (0.52) | DPP4MAPTLMNASUV39H2L3MBTL1 | |
| SCHEMBL29087311 | 0.75 | NOTUM (0.52) | DPP4MAPTLMNASUV39H2L3MBTL1 | |
| SCHEMBL383362 | 0.73 | PRKD3 (0.56) | PRKD3MAP4K4PIM1CLK2MAP4K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |