Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 4/20 | 0.85 |
| ▸ | CCR3 | P51677 | 3/20 | 0.70 |
| ▸ | CCR1 | P32246 | 7/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712812 | 0.92 | KCNA3 (1.00) | KCNA3CCR3CCR1SIGMAR1RAB9A | |
| SCHEMBL7526133 | 0.92 | KCNA3 (0.72) | KCNA3CCR3CCR1 | |
| SCHEMBL9103936 | 0.85 | KCNA3 (0.85) | KCNA3CCR3CCR1 | |
| SCHEMBL904831 | 0.80 | CCR3 (0.64) | KCNA3CCR3CCR1RAB9ANPSR1 | |
| SCHEMBL904837 | 0.80 | ADRA1D (0.62) | KCNA3CCR3 | |
| SCHEMBL904843 | 0.79 | CCR3 (0.56) | KCNA3CCR3CCR1 | |
| SCHEMBL904913 | 0.79 | CCR3 (0.56) | KCNA3CCR3CCR1 | |
| SCHEMBL904841 | 0.79 | CCR3 (0.56) | KCNA3CCR3CCR1 | |
| Hydrochloric Acid SCHEMBL11627731 | 0.78 | CCR3 (0.62) | KCNA3CCR3CCR1RAB9ANPSR1 | |
| SCHEMBL7461929 | 0.78 | SIGMAR1 (0.57) | KCNA3CCR3CCR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |