Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.56 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399328 | 0.82 | DRD2 (0.65) | DRD2DRD4GRM2SMN1; SMN2LMNA | |
| SCHEMBL7533466 | 0.80 | DRD2 (0.60) | DRD2DRD4GRM2SMN1; SMN2LMNA | |
| SCHEMBL7470794 | 0.79 | KCNA3 (0.85) | CCR3KCNA3CCR1 | |
| SCHEMBL14463703 | 0.78 | DRD2 (0.63) | DRD2DRD4GRM2SMN1; SMN2LMNA | |
| SCHEMBL904841 | 0.78 | CCR3 (0.56) | CCR3KCNA3LMNACCR1 | |
| SCHEMBL904913 | 0.78 | CCR3 (0.56) | CCR3KCNA3CCR1 | |
| SCHEMBL8025525 | 0.77 | DRD2 (0.58) | DRD2DRD4GRM2SMN1; SMN2LMNA | |
| SCHEMBL31145168 | 0.77 | DRD2 (0.58) | DRD2DRD4GRM2SMN1; SMN2LMNA | |
| SCHEMBL7999797 | 0.75 | DRD2 (0.54) | DRD2DRD4GRM2SMN1; SMN2LMNA | |
| SCHEMBL9103936 | 0.75 | KCNA3 (0.85) | CCR3KCNA3CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |