Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462734 | 0.90 | EGFR (0.55) | EGFRHTTNTRK1CNR1CNR2 | |
| SCHEMBL7469106 | 0.90 | CLK4 (0.58) | EGFRCLK4HTTCNR1CNR2 | |
| SCHEMBL7464363 | 0.89 | HTT (0.54) | EGFRHTTNTRK1CNR1CNR2 | |
| SCHEMBL7474181 | 0.89 | MAPK1 (0.56) | EGFRHTTCNR1CNR2MAPT | |
| SCHEMBL7467508 | 0.85 | MAPK1 (0.52) | EGFRCLK4HTTMAPTMAPK1 | |
| SCHEMBL7469664 | 0.84 | HTT (0.63) | EGFRHTTNTRK1CNR1CNR2 | |
| SCHEMBL7467125 | 0.84 | EGFR (0.51) | EGFRCLK4HTTCNR1CNR2 | |
| SCHEMBL7469795 | 0.83 | EGFR (0.60) | EGFRHTTNTRK1CNR1CNR2 | |
| SCHEMBL7528662 | 0.83 | EGFR (0.52) | EGFRHTTNTRK1CNR1CNR2 | |
| SCHEMBL7474806 | 0.83 | EGFR (0.52) | EGFRHTTNTRK1PRKCQMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |