SCHEMBL7470835

SCHEMBL7470835

CCOC(=O)c1cccc(OC(F)(F)F)c1.O=S(=O)(O)Cl

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 2/20 0.49
KAT6A Q92794 4/20 0.47
ELANE P08246 2/20 0.47
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45
F10 P00742 1/20 0.45
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5456700 0.92 ELANE (0.52) ELANECYP4F2CYP4A11F10MEN1
SCHEMBL7468451 0.90 ALDH1A1 (0.51) DDR1KAT6AELANEMEN1KMT2A
SCHEMBL7464613 0.87 LMNA (0.53) CYP4F2CYP4A11F10MEN1MAPT
SCHEMBL27516867 0.86 ALDH1A1 (0.52) DDR1KAT6AMEN1KMT2AHDAC8
SCHEMBL7475996 0.85 SMN1; SMN2 (0.56) ELANEMEN1MAPTKMT2A
SCHEMBL7468439 0.85 MRGPRX4 (0.55) DDR1KAT6AHDAC8
SCHEMBL7471216 0.84 MAPT (0.54) CYP4F2CYP4A11MEN1MAPTKMT2A
SCHEMBL7471424 0.82 HDAC8 (0.52) DDR1KAT6AELANEMEN1MAPT
SCHEMBL7471102 0.81 POLB (0.54) ELANECYP4F2CYP4A11CA12CA1
SCHEMBL29035735 0.81 ALDH1A1 (0.58) KAT6AMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed