Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470761 | 0.88 | MAPT (0.42) | ALOX15TSHRMEN1KMT2ANPC1 | |
| SCHEMBL7470170 | 0.78 | NR4A2 (0.56) | KMT2ANPC1RAB9AMRGPRX4 | |
| SCHEMBL29159768 | 0.73 | MMP13 (0.49) | KDM4ENPC1RAB9AMAPTMMP1 | |
| SCHEMBL7471939 | 0.72 | MRGPRX4 (0.41) | KDM4ETSHRTDP1MEN1KMT2A | |
| SCHEMBL8623878 | 0.72 | PTGER1 (0.62) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL29683116 | 0.72 | MAPK8 (0.55) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL12168624 | 0.72 | MAPK8 (0.55) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL27945865 | 0.72 | KDM4E (0.47) | ECE1KDM4EALOX15TSHRACMSD | |
| SCHEMBL7477249 | 0.71 | MAPT (0.46) | KMT2ANPC1RAB9AMAPTHSP90AA1 | |
| SCHEMBL7471261 | 0.71 | CA12 (0.49) | TSHRPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786457-B1 | AZOLE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5981559-A | USEFUL IN PREVENTING OR TREATING ALLERGIC DISEASES, ISCHEMIC HEART DISEASES OR ISCHEMIC BRAIN DISEASES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0786457-A1 | AZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |