Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | YAP1 | P46937 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470036 | 0.93 | YAP1 (0.34) | HDAC1HDAC6YAP1TACR1TLR9 | |
| SCHEMBL7474754 | 0.93 | TACR1 (0.33) | YAP1TACR1TLR9TLR7MRGPRX4 | |
| SCHEMBL7463404 | 0.91 | YAP1 (0.33) | HDAC1HDAC6YAP1TACR1TLR9 | |
| SCHEMBL7460836 | 0.86 | TACR1 (0.34) | YAP1TACR1TLR9TLR7GHSR | |
| SCHEMBL7466465 | 0.84 | TACR1 (0.32) | YAP1TACR1TLR9TLR7GHSR | |
| SCHEMBL7474530 | 0.84 | ADH1A (0.34) | HDAC1HDAC6 | |
| SCHEMBL7466119 | 0.82 | — | — | |
| SCHEMBL9367604 | 0.81 | YAP1 (0.35) | HDAC1HDAC6YAP1TLR9TLR7 | |
| SCHEMBL7482550 | 0.80 | TLR9 (0.34) | YAP1TLR9TLR7GHSRMEN1 | |
| SCHEMBL16941959 | 0.80 | TLR9 (0.34) | YAP1TLR9TLR7GHSRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656360-B1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5629430-A | ANTICARCINOGENIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0656360-A1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |