Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463404 | 0.91 | YAP1 (0.33) | YAP1TLR9TLR7HDAC1HDAC6 | |
| SCHEMBL7466465 | 0.85 | TACR1 (0.32) | YAP1TLR9TLR7L3MBTL1PTGER1 | |
| SCHEMBL7470036 | 0.82 | YAP1 (0.34) | YAP1TLR9TLR7HDAC1HDAC6 | |
| SCHEMBL7470902 | 0.81 | HDAC1 (0.34) | YAP1TLR9TLR7HDAC1HDAC6 | |
| SCHEMBL6995739 | 0.81 | SRD5A2 (0.40) | YAP1TLR9TLR7CYP2C9GHSR | |
| SCHEMBL9615143 | 0.77 | PRKCA (0.35) | YAP1TLR9TLR7MEN1MAPT | |
| SCHEMBL5865450 | 0.77 | TLR9 (0.37) | YAP1TLR9TLR7GHSR | |
| SCHEMBL7460836 | 0.76 | TACR1 (0.34) | YAP1TLR9TLR7MEN1MAPT | |
| SCHEMBL7474754 | 0.76 | TACR1 (0.33) | YAP1TLR9TLR7MAPK1MEN1 | |
| SCHEMBL6997323 | 0.75 | GHSR (0.38) | YAP1TLR9TLR7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6116270-A | — | — | None | — | — | JP | disclosed |
| JP-H06116270-A | TETRAHYDROPYRROLOINDOLE DERIVATIVE, ITS PRODUCTION AND INTERMEDIATE THEREFOR | KYORIN PHARMACEUT CO LTD | 1994-04-26 | — | — | JP | disclosed |