Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470989 | 1.00 | ALDH1A1 (0.35) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8569842 | 0.87 | — | — | |
| SCHEMBL8569840 | 0.87 | — | — | |
| SCHEMBL7464751 | 0.84 | — | — | |
| SCHEMBL7464742 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL5995504 | 0.82 | — | — | |
| SCHEMBL8763397 | 0.82 | — | — | |
| SCHEMBL7470094 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7469956 | 0.82 | — | — | |
| SCHEMBL7470099 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764648-B1 | Cephem derivatives and process for the preparation thereof | EISAI CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| EP-0333154-B1 | Process for the preparation of cephem derivatives | EISAI CO LTD (JP) | 1997-07-16 | — | — | EP | disclosed |
| EP-0764648-A1 | Cephem derivatives and process for the preparation thereof | Eisai Co., Ltd. (JP) | 1997-03-26 | — | — | EP | disclosed |
| EP-0287116-B1 | Thiadiazolylacetamide cephem derivatives | EISAI CO LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0612751-A2 | Compounds for the preparation of cephem derivatives | Eisai Co., Ltd. (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5128465-A | Containing thiadiazole ring and fluorine substitution | EISAI CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5089491-A | Active against both gram-negative and gram-positive bacteria | EISAI CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |
| EP-0264091-B1 | 3-PROPENYLCEPHEM DERIVATIVE, PREPARATION THEREOF, CHEMICAL INTERMEDIATES THEREIN, PHARMACEUTICAL COMPOSITION AND USE | Eisai Co., Ltd. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-5066812-A | Chemical intermediates for bactericides | EISAI CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| US-5006649-A | Bactericides | EISAI, CO. (JP) | 1991-04-09 | — | — | US | disclosed |
| US-4929612-A | ANTIBIOTICS, BACTERICIDES | EISAI CO., LTD. (JP) | 1990-05-29 | — | — | US | disclosed |
| US-4921850-A | GRAMNEGATIVE AND GRAMPOSITIVE BACTERICIDE | EISAI CO., LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0333154-A2 | Process for the preparation of cephem derivatives and intermediates therefor | Eisai Co., Ltd. (JP) | 1989-09-20 | — | — | EP | disclosed |
| EP-0287116-A2 | Thiadiazolylacetamide cephem derivatives | Eisai Co., Ltd. (JP) | 1988-10-19 | — | — | EP | disclosed |
| EP-0264091-A2 | 3-Propenylcephem derivative, preparation thereof, chemical intermediates therein, pharmaceutical composition and use | Eisai Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |