Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | COMT | P21964 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | HCK | P08631 | 1/20 | 0.45 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759857 | 0.76 | ABL1 (0.56) | MEN1KMT2AKCNK3KCNK9HCK | |
| SCHEMBL6834840 | 0.75 | FYN (0.51) | MEN1KMT2AMAPTKCNK3KCNK9 | |
| SCHEMBL6803237 | 0.74 | CSF1R (0.44) | MEN1KMT2AMAPTPOLBKCNK3 | |
| SCHEMBL7984140 | 0.74 | ALDH1A1 (0.58) | MEN1KMT2ACOMTMMP2MMP9 | |
| SCHEMBL6759881 | 0.73 | EPHA2 (0.49) | MEN1KMT2AMAPTKCNK3KCNK9 | |
| SCHEMBL27519956 | 0.73 | HCK (0.48) | MEN1KMT2AMAPTPOLBKCNK3 | |
| SCHEMBL592446 | 0.71 | NQO2 (0.66) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL7979817 | 0.70 | CYP1A2 (0.51) | MEN1KMT2ACOMTMMP2MMP9 | |
| SCHEMBL27824615 | 0.70 | MAPT (0.47) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL6756711 | 0.70 | FYN (0.48) | HCKNR2C2BTKHTR1AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216240-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001025229-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-12 | — | — | WO | disclosed |