Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.44 |
| ▸ | KIT | P10721 | 4/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | HCK | P08631 | 3/20 | 0.44 |
| ▸ | NR2C2 | P49116 | 3/20 | 0.44 |
| ▸ | BTK | Q06187 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27519956 | 0.85 | HCK (0.48) | CSF1RKITKCNK3KCNK9HCK | |
| SCHEMBL6757923 | 0.78 | MEN1 (0.49) | CSF1RKITKCNK3KCNK9HCK | |
| SCHEMBL6834840 | 0.77 | FYN (0.51) | CSF1RKITKCNK3KCNK9HCK | |
| SCHEMBL7471000 | 0.74 | MEN1 (0.48) | CSF1RKITKCNK3KCNK9HCK | |
| SCHEMBL6759881 | 0.74 | EPHA2 (0.49) | CSF1RKITKCNK3KCNK9HCK | |
| SCHEMBL6759857 | 0.73 | ABL1 (0.56) | KCNK3KCNK9HCKNR2C2BTK | |
| SCHEMBL6756711 | 0.72 | FYN (0.48) | CSF1RKITHCKNR2C2BTK | |
| SCHEMBL7118424 | 0.72 | ALDH1A1 (0.58) | MEN1KMT2APOLBMAPT | |
| SCHEMBL2337472 | 0.72 | RIPK1 (0.51) | MEN1KMT2AMAPT | |
| SCHEMBL7120206 | 0.69 | CYP1A2 (0.51) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266774-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-30 | — | — | US | disclosed |
| US-6770667-B1 | N-((IMIDAZOLYL)-PHENYL)-FLUORENE-1-CARBOXAMIDE DERIVATIVES; 5-HYDROXYTRYPTAMINE (5-HT) ANTAGONISTS; PSYCHOLOGICAL, NERVOUS SYSTEM, EATING, BRAIN AND SLEEP DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266774-A1 | Amide compounds | TPH1, HTR1A, HTR5A | CSF1R 2490/4885KIT 870/4885KCNK3 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.