SCHEMBL6834840

SCHEMBL6834840

Cc1ncc(-c2cccc(NC(=O)c3cccc(-c4cccs4)c3)c2)n1C

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FYN P06241 5/20 0.51
GRK5 P34947 1/20 0.48
CSF1R P07333 3/20 0.47
KIT P10721 3/20 0.47
HCK P08631 1/20 0.46
NR2C2 P49116 1/20 0.46
BTK Q06187 1/20 0.46
CAMK2D Q13557 5/20 0.46
EPHA2 P29317 1/20 0.45
KCNK3 O14649 1/20 0.45
KCNK9 Q9NPC2 1/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
HTR1A P08908 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
CCKAR P32238 1/20 0.44
HTR5A P47898 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6759881 0.88 EPHA2 (0.49) FYNGRK5CSF1RKITHCK
SCHEMBL6756711 0.87 FYN (0.48) FYNGRK5CSF1RKITHCK
SCHEMBL6757951 0.84 DYRK1A (0.46) FYNMEN1MAPTKMT2A
SCHEMBL6799452 0.84 FYN (0.49) FYNMAPT
SCHEMBL7120246 0.82 FYN (0.47) FYNGRK5MEN1MAPTKMT2A
SCHEMBL6804624 0.82 DYRK1A (0.57) FYNBTKMEN1MAPTKMT2A
SCHEMBL27519956 0.78 HCK (0.48) CSF1RKITHCKNR2C2BTK
SCHEMBL6759857 0.78 ABL1 (0.56) HCKNR2C2BTKEPHA2KCNK3
SCHEMBL6803237 0.77 CSF1R (0.44) CSF1RKITHCKNR2C2BTK
SCHEMBL6808846 0.76 MAPT (0.63) MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040266774-A1 Amide compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040266774-A1 Amide compounds TPH1, HTR1A, HTR5A FYN 2025/4885GRK5 68/4885CSF1R 2490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.