Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.47 |
| ▸ | ADH1C | P00326 | 1/20 | 0.47 |
| ▸ | ADH1A | P07327 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190837 | 0.82 | HSD11B1 (0.47) | HSD11B1KDM4DASGR1PDE10AKAT6A | |
| SCHEMBL2678855 | 0.79 | HSD11B1 (0.39) | HSD11B1KDM4DASGR1PDE10AKAT6A | |
| SCHEMBL4803692 | 0.78 | HSD11B1 (0.40) | HSD11B1KDM4DASGR1PDE10AKAT6A | |
| SCHEMBL4804112 | 0.78 | HSD11B1 (0.40) | HSD11B1KDM4DASGR1PDE10AKAT6A | |
| Formic Acid SCHEMBL27813341 | 0.78 | HSD11B1 (0.42) | ADH1CADH1AHSD11B1KDM4DASGR1 | |
| SCHEMBL7498978 | 0.78 | ADH1C (0.56) | ADH1BADH1CADH1A | |
| SCHEMBL28804053 | 0.77 | HSD11B1 (0.44) | HSD11B1KDM4DASGR1PDE10AKAT6A | |
| SCHEMBL28804055 | 0.77 | HSD11B1 (0.44) | HSD11B1KDM4DASGR1PDE10AKAT6A | |
| SCHEMBL228179 | 0.77 | HSD11B1 (0.46) | HSD11B1KDM4DASGR1PDE10A | |
| SCHEMBL7816804 | 0.77 | HSD11B1 (0.40) | HSD11B1KDM4DASGR1PDE10AKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183245-A4 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMA CORP (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-1194421-A4 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMA CORP (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1194421-A1 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2002-04-10 | — | — | EP | disclosed |
| EP-1183245-A1 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2001002379-A1 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2000064880-A1 | SELECTIVE NPY (Y5) ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-11-02 | — | — | WO | disclosed |