Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23841944 | 0.89 | HSD11B1 (0.40) | HSD11B1ASGR1KDM4DDPP4DPP8 | |
| SCHEMBL190837 | 0.86 | HSD11B1 (0.47) | HSD11B1ASGR1KDM4DKAT6AKAT8 | |
| SCHEMBL15739423 | 0.83 | HSD11B1 (0.41) | HSD11B1ASGR1KDM4D | |
| SCHEMBL28804053 | 0.81 | HSD11B1 (0.44) | HSD11B1ASGR1KDM4DKAT6AKAT8 | |
| SCHEMBL28804055 | 0.81 | HSD11B1 (0.44) | HSD11B1ASGR1KDM4DKAT6AKAT8 | |
| SCHEMBL228179 | 0.81 | HSD11B1 (0.46) | HSD11B1ASGR1KDM4DPDE10A | |
| SCHEMBL17173156 | 0.80 | HSD11B1 (0.41) | HSD11B1ASGR1KDM4D | |
| SCHEMBL17173155 | 0.80 | HSD11B1 (0.41) | HSD11B1ASGR1KDM4D | |
| SCHEMBL7808569 | 0.80 | HSD11B1 (0.36) | HSD11B1ASGR1KDM4D | |
| SCHEMBL1204992 | 0.80 | HSD11B1 (0.43) | HSD11B1ASGR1KDM4DKAT6AKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798298-B1 | THIAZOLIDINONE OR OXAZOLIDINONE DERIVATIVES TO TREAT ANGINA PECTORIS OR COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO CO (JP) | 2001-08-08 | — | — | EP | disclosed |
| US-5843973-A | Thiazolidinone compounds and composition for angina pectoris comprising the compounds as an active ingredient | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0798298-A1 | THIAZOLIDINONE COMPOUNDS OR ANGINA PECTORIS REMEDY OR PREVENTIVE CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO COMPANY LIMITED (JP) | 1997-10-01 | — | — | EP | disclosed |