Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255865 | 0.89 | LOXL2 (0.43) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL7364038 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL11060991 | 0.82 | ALDH1A1 (0.61) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL28161942 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL30814185 | 0.78 | KMT2A (0.57) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL7094868 | 0.77 | ALDH1A1 (0.67) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL351920 | 0.77 | HRH1 (0.65) | ALDH1A1CYP3A4TDP1HRH1HRH4 | |
| SCHEMBL7093157 | 0.75 | ALDH1A1 (0.70) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL31673871 | 0.75 | HRH1 (0.62) | ALDH1A1CYP3A4TDP1HRH1HRH4 | |
| SCHEMBL28055322 | 0.75 | HRH1 (0.62) | ALDH1A1CYP3A4TDP1HRH1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-B1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMA (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6458959-B1 | VIRICIDES AND ENZYME INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-10-01 | — | — | US | disclosed |
| US-6348477-B1 | SUBSTITUTED PHENYL THIAZOLE DERIVATIVES AS VIRICIDES | BOEHRINGER INGELHEIM(CANADA) LTD. (CA) | 2002-02-19 | — | — | US | disclosed |
| US-6057451-A | AMINOTHIAZOLE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |