Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.62 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.60 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.60 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PTPRB | P23467 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27425792 | 0.95 | LOXL2 (0.64) | LOXL2CYP4F2CYP4A11SLC7A5POLB | |
| SCHEMBL126284 | 0.90 | LOXL2 (0.74) | LOXL2CYP4F2CYP4A11SLC7A5POLB | |
| SCHEMBL7473301 | 0.86 | CYP4F2 (0.61) | CYP4F2CYP4A11MAPTALDH1A1RAB9A | |
| SCHEMBL5969642 | 0.84 | LOXL2 (0.62) | LOXL2CYP4F2CYP4A11SLC7A5POLB | |
| Hydroquinone SCHEMBL28832812 | 0.84 | LOXL2 (0.66) | LOXL2CYP4F2CYP4A11SLC7A5MRGPRX4 | |
| SCHEMBL3932525 | 0.84 | LOXL2 (0.66) | LOXL2CYP4F2CYP4A11SLC7A5POLB | |
| SCHEMBL7474110 | 0.84 | NPC1 (0.48) | LOXL2CYP4F2CYP4A11SLC7A5POLB | |
| SCHEMBL7464858 | 0.84 | LMNA (0.55) | LOXL2CYP4F2CYP4A11SLC7A5POLB | |
| SCHEMBL7472745 | 0.83 | POLB (0.53) | LOXL2CYP4F2CYP4A11POLBMAPT | |
| SCHEMBL7467547 | 0.82 | POLB (0.55) | LOXL2CYP4F2CYP4A11POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859774-B1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |
| EP-0859774-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997016449-A1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-09 | — | — | WO | disclosed |