Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TACR3 | P29371 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352428 | 0.84 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1TDP1KMT2ATACR3 | |
| SCHEMBL28703250 | 0.81 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1TDP1KMT2ATACR3 | |
| SCHEMBL4241780 | 0.81 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1TDP1KMT2ATACR3 | |
| SCHEMBL28019223 | 0.79 | NPSR1 (0.50) | ALDH1A1L3MBTL1TDP1KMT2AMAPT | |
| SCHEMBL5624200 | 0.79 | TDP1 (0.46) | ALDH1A1L3MBTL1TDP1KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL4233000 | 0.78 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1TDP1KMT2ATACR3 | |
| SCHEMBL7417080 | 0.78 | TDP1 (0.44) | ALDH1A1L3MBTL1TDP1KMT2AMAPT | |
| SCHEMBL9631330 | 0.77 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1TDP1KMT2ATACR3 | |
| SCHEMBL4107497 | 0.76 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1TDP1KMT2AMAPT | |
| SCHEMBL5696331 | 0.75 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1TDP1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923562-B1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AG (DE) | 2002-10-09 | — | — | EP | disclosed |
| US-6444616-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-6130225-A | Substituted p-trifluoromethylphenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-10 | — | — | US | disclosed |
| EP-0923562-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006706-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-19 | — | — | WO | disclosed |