Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TACR3 | P29371 | 10/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29899039 | 0.84 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL28352428 | 0.80 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL16236160 | 0.79 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7472041 | 0.77 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL28703250 | 0.77 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL4241780 | 0.77 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KMT2ATDP1SMN1; SMN2 | |
| Acetic Acid SCHEMBL8462148 | 0.75 | ATM (0.41) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2MAPT | |
| Methyl Alcohol SCHEMBL27709287 | 0.71 | ATM (0.41) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL10722115 | 0.71 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL5696331 | 0.71 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324988-B1 | 4-CHLOR-3-SULFAMOYL BENZOIC ACID HYDRAZIDES, PROCESS FOR THEIR PREPARATION, MEDICINES CONTAINING THEM AND USE OF THESE COMPOUNDS IN THE PREPARATION OF DIURETIC AND SALT REDUCING ACTIVITY MEDICINES | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1992-04-29 | — | — | EP | disclosed |
| EP-0324988-A1 | 4-Chlor-3-sulfamoyl benzoic acid hydrazides, process for their preparation, medicines containing them and use of these compounds in the preparation of diuretic and salt reducing activity medicines | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1989-07-26 | — | — | EP | disclosed |