Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140669 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL19007858 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL25735491 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL21319327 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL13880234 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL28747000 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL24235719 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL7365728 | 0.84 | SLC15A1 (0.57) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL22607077 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL4890742 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |