Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472117 | 0.83 | MIF (0.38) | MIFESR1ESR2CTSSCTSK | |
| SCHEMBL7472114 | 0.80 | PRSS1 (0.38) | MIFLY96ESR1ESR2CTSS | |
| SCHEMBL8550167 | 0.80 | SMN1; SMN2 (0.43) | ESR1LTA4HTSHRMAPK1 | |
| SCHEMBL15962588 | 0.78 | CTSS (0.49) | MIFLY96ESR1ESR2CTSS | |
| SCHEMBL27747410 | 0.73 | MIF (0.39) | MIFLY96ESR1ESR2CTSS | |
| SCHEMBL5414405 | 0.72 | MIF (0.40) | MIFESR1ESR2CTSSCTSK | |
| SCHEMBL5414409 | 0.72 | MIF (0.40) | MIFESR1ESR2CTSSCTSK | |
| SCHEMBL9995953 | 0.72 | MIF (0.40) | MIFESR1ESR2CTSSCTSK | |
| SCHEMBL2582580 | 0.72 | CTSS (0.48) | MIFESR1ESR2CTSSCTSK | |
| SCHEMBL1554126 | 0.72 | CTSS (0.48) | MIFESR1ESR2CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |