Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601269 | 0.83 | MIF (0.36) | MIFESR1ESR2KMT2AMAPK1 | |
| SCHEMBL5414409 | 0.79 | MIF (0.40) | MIFESR1ESR2LMNAKMT2A | |
| SCHEMBL9995953 | 0.79 | MIF (0.40) | MIFESR1ESR2LMNAKMT2A | |
| SCHEMBL5414405 | 0.79 | MIF (0.40) | MIFESR1ESR2LMNAKMT2A | |
| SCHEMBL11525093 | 0.78 | KMT2A (0.43) | MIFESR1ESR2LMNAKMT2A | |
| SCHEMBL27747410 | 0.78 | MIF (0.39) | MIFESR1ESR2LMNAKMT2A | |
| SCHEMBL3525216 | 0.76 | ACHE (0.39) | MIFESR1ESR2LMNAKMT2A | |
| SCHEMBL7467555 | 0.75 | ESR1 (0.41) | MIFESR1ESR2AAK1LMNA | |
| SCHEMBL10618816 | 0.75 | MIF (0.41) | MIFESR1ESR2LMNAKMT2A | |
| SCHEMBL27455879 | 0.75 | LMNA (0.38) | MIFESR1ESR2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |