Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472130 | 1.00 | LMNA (0.47) | LMNAKMT2ATP53MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6836957 | 0.99 | LMNA (0.46) | LMNAKMT2ATP53MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6836953 | 0.99 | LMNA (0.46) | LMNAKMT2ATP53MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6844604 | 0.88 | NFE2L2 (0.43) | LMNAKMT2ATP53MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6836865 | 0.88 | NFE2L2 (0.43) | LMNAKMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL7473227 | 0.87 | RAB9A (0.42) | LMNAKMT2ATP53MAPTKDM4E | |
| SCHEMBL7473215 | 0.87 | RAB9A (0.42) | LMNAKMT2ATP53MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6836924 | 0.86 | RAB9A (0.41) | LMNAKMT2ATP53MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6839856 | 0.86 | RAB9A (0.41) | LMNAKMT2ATP53MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6832793 | 0.84 | KMT2A (0.44) | LMNAKMT2ATP53MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937722-B1 | Benzimidazole derivatives as cyclooxygenase-2 inhibitors | PFIZER (US) | 2002-07-03 | — | — | EP | claimed |