Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358244 | 0.86 | TSHR (0.37) | TSHRALOX15THRBCHRM2CHRM4 | |
| SCHEMBL4453590 | 0.82 | ALDH1A1 (0.52) | ACHETSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL1017382 | 0.82 | ALDH1A1 (0.52) | ACHETSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL3358255 | 0.81 | ALOX15 (0.48) | TSHRALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9003084 | 0.81 | ALOX15 (0.48) | TSHRALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL27544358 | 0.79 | CHRM1 (0.46) | ACHETHRBCHRM2CHRM4CHRM5 | |
| SCHEMBL21814420 | 0.79 | TSHR (0.58) | ACHETSHRALDH1A1LMNA | |
| SCHEMBL27861651 | 0.79 | ACHE (0.37) | ACHETSHRTHRBCHRM5CHRM1 | |
| SCHEMBL27716578 | 0.79 | ACHE (0.37) | ACHETSHRTHRBCHRM5CHRM1 | |
| SCHEMBL27745731 | 0.78 | CHRM2 (0.32) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996652-B1 | TWO-PACKAGE WATERBORNE URETHANE COATINGS | DU PONT (US) | 2002-12-11 | — | — | EP | disclosed |
| US-6239214-B1 | MACROMONOMER COMPRISING AT LEAST ABOUT 5 WEIGHT PERCENT OF AN UNSATURATED ACID-FUNCTIONAL MONOMER PREPARED USING A COBALT-BASED CATALYTIC CHAIN TRANSFER AGENT | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-05-29 | — | — | US | disclosed |
| EP-0996652-A1 | TWO-PACKAGE WATERBORNE URETHANE COATINGS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999003905-A1 | GRAFT COPOLYMER EMULSIONS AND TWO-PACKAGE WATERBORNE URETHANE COATINGS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-01-28 | — | — | WO | disclosed |