Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.44 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17516330 | 0.82 | LMNA (0.47) | KIF11CRHBPCRHR2ESR1ESR2 | |
| SCHEMBL11077265 | 0.82 | KIF11 (0.60) | KIF11CRHBPCRHR2ESR1ESR2 | |
| SCHEMBL7398535 | 0.81 | CRHBP (0.48) | KIF11CRHBPCRHR2ESR1ESR2 | |
| SCHEMBL15779834 | 0.81 | CRHBP (0.48) | KIF11CRHBPCRHR2ESR1ESR2 | |
| SCHEMBL27623049 | 0.79 | KIF11 (0.43) | KIF11CRHBPCRHR2ESR1ESR2 | |
| SCHEMBL6375764 | 0.79 | ESR1 (0.52) | KIF11CRHBPCRHR2ESR1ESR2 | |
| SCHEMBL28478636 | 0.79 | ESR1 (0.52) | KIF11CRHBPCRHR2ESR1ESR2 | |
| SCHEMBL6377979 | 0.79 | ESR1 (0.52) | KIF11CRHBPCRHR2ESR1ESR2 | |
| SCHEMBL6375768 | 0.79 | ESR1 (0.52) | KIF11CRHBPCRHR2ESR1ESR2 | |
| SCHEMBL27305720 | 0.78 | CRHBP (0.46) | KIF11CRHBPCRHR2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |