Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474272 | 0.77 | KMT2A (0.38) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL6241617 | 0.77 | KDM4E (0.44) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL7474776 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CFTRMAPTKDM4EHPGD | |
| SCHEMBL7474993 | 0.74 | SMN1; SMN2 (0.38) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7478693 | 0.73 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7476393 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAHTTNPC1 | |
| SCHEMBL15983589 | 0.67 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPTKDM4EUSP2 | |
| SCHEMBL3470351 | 0.65 | CFTR (0.57) | ALDH1A1TSHRCFTRMAPTHPGD | |
| SCHEMBL15983573 | 0.65 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTKDM4EUSP2 | |
| SCHEMBL15837498 | 0.63 | TSHR (0.74) | ALDH1A1TSHRMAPTKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219608-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING THE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219608-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING THE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |