Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474272 | 0.88 | KMT2A (0.38) | ALDH1A1APOBEC3GMAPTHPGDHSD17B10 | |
| SCHEMBL6241617 | 0.81 | KDM4E (0.44) | ALDH1A1L3MBTL1HPGDHSD17B10KDM4E | |
| SCHEMBL7965028 | 0.79 | ALDH1A1 (0.47) | ALDH1A1ADORA2BL3MBTL1MAPTHPGD | |
| SCHEMBL7474993 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1L3MBTL1MAPTKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL7962958 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ADORA2BL3MBTL1MAPTHPGD | |
| SCHEMBL7478693 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MAPTHSD17B10KDM4EKMT2A | |
| SCHEMBL7961174 | 0.76 | ALDH1A1 (0.45) | ALDH1A1ADORA2BL3MBTL1MAPTHPGD | |
| SCHEMBL7293146 | 0.76 | ALDH1A1 (0.48) | ALDH1A1ADORA2BL3MBTL1MAPTHPGD | |
| SCHEMBL7472903 | 0.76 | ALDH1A1 (0.56) | ALDH1A1CFTRMAPTHPGDHSD17B10 | |
| SCHEMBL7962214 | 0.74 | ALDH1A1 (0.46) | ALDH1A1APOBEC3GADORA2BL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219608-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING THE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |