Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241617 | 0.84 | KDM4E (0.44) | EGFRERBB2MEN1KMT2ARAB9A | |
| SCHEMBL7474272 | 0.79 | KMT2A (0.38) | SMN1; SMN2MEN1KMT2ARAB9ALMNA | |
| SCHEMBL7476393 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2RAB9AL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL7474776 | 0.78 | ALDH1A1 (0.46) | MEN1KMT2ARAB9APOLBL3MBTL1 | |
| SCHEMBL7478693 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2MEN1KMT2ARAB9APOLB | |
| SCHEMBL7472903 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2MEN1KMT2ALMNAPOLB | |
| SCHEMBL6803122 | 0.63 | CMA1 (0.52) | MEN1KMT2ARAB9ATDP1ALDH1A1 | |
| SCHEMBL25335381 | 0.62 | CRHBP (0.49) | SMN1; SMN2MEN1KMT2ARAB9ALMNA | |
| SCHEMBL30765677 | 0.62 | KDM4E (0.49) | L3MBTL1ALDH1A1ELANECYP1A2CYP2C9 | |
| SCHEMBL17111627 | 0.62 | MAPK1 (0.45) | SMN1; SMN2MEN1KMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219608-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING THE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |