Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | PRCP | P42785 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618383 | 0.78 | PRCP (0.35) | OPRM1OPRK1PRCPMAPTOPRD1 | |
| SCHEMBL7207522 | 0.70 | MEN1 (0.31) | MAPTALDH1A1NPSR1 | |
| SCHEMBL7207966 | 0.69 | KMT2A (0.51) | — | |
| SCHEMBL7483876 | 0.66 | KMT2A (0.45) | — | |
| SCHEMBL7482639 | 0.66 | KMT2A (0.42) | ALDH1A1TSHR | |
| SCHEMBL7207584 | 0.64 | DRD2 (0.47) | MAPTALDH1A1 | |
| SCHEMBL11725532 | 0.63 | OPRM1 (0.47) | OPRM1OPRK1PRCPTSHRNPSR1 | |
| SCHEMBL11793680 | 0.62 | PRCP (0.56) | OPRM1PRCPMAPTALDH1A1SLC22A1 | |
| SCHEMBL7467290 | 0.62 | — | — | |
| SCHEMBL11849339 | 0.60 | PRCP (0.56) | PRCPSLC22A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923551-B1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PROD (US) | 2002-06-05 | — | — | EP | disclosed |
| EP-0923551-A1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008819-A1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-05 | — | — | WO | disclosed |