Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752447 | 0.75 | CYP19A1 (0.69) | CYP19A1PTGES2ACLYSLC40A1HDAC3 | |
| SCHEMBL6416265 | 0.74 | MMP3 (0.60) | MMP3MMP2MMP9MMP13ALDH1A1 | |
| SCHEMBL6416258 | 0.74 | MMP3 (0.60) | MMP3MMP2MMP9MMP13ALDH1A1 | |
| SCHEMBL7468288 | 0.74 | MMP3 (0.47) | MMP3MMP2MMP9MMP13SMN1; SMN2 | |
| SCHEMBL19381716 | 0.72 | HTR1A (0.47) | KDM4ETP53ALDH1A1GAAHTR6 | |
| SCHEMBL4431378 | 0.72 | MMP3 (0.70) | MMP3MMP2MMP9MMP13ALDH1A1 | |
| SCHEMBL4431389 | 0.72 | MMP3 (0.70) | MMP3MMP2MMP9MMP13ALDH1A1 | |
| SCHEMBL6418278 | 0.72 | MMP3 (0.70) | MMP3MMP2MMP9MMP13ALDH1A1 | |
| SCHEMBL4426623 | 0.71 | MMP3 (0.54) | MMP3MMP2MMP9MMP13SMN1; SMN2 | |
| SCHEMBL3107582 | 0.71 | MMP2 (0.46) | MMP3MMP2MMP9MMP13SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874836-B1 | SULFONAMIDE INHIBITORS OF MATRIX METALLOPROTEINASES | WARNER LAMBERT CO (US) | 2002-10-09 | — | — | EP | disclosed |