Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273252 | 0.82 | HSP90AA1 (0.56) | NSD2KMT2AHPGDALDH1A1GAA | |
| SCHEMBL2236766 | 0.81 | HPGD (0.77) | NSD2KMT2AHPGDKDM4EALDH1A1 | |
| Glycine SCHEMBL29048907 | 0.76 | HPGD (0.68) | NSD2KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL31680569 | 0.75 | KMT2A (0.89) | NSD2KMT2AHPGDGAALMNA | |
| SCHEMBL11901003 | 0.75 | KMT2A (0.89) | NSD2KMT2AHPGDGAALMNA | |
| SCHEMBL17774887 | 0.75 | NSD2 (0.58) | NSD2KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL1900238 | 0.74 | HDAC6 (0.67) | HPGDKDM4ELMNATP53HDAC2 | |
| SCHEMBL11403224 | 0.74 | NSD2 (0.85) | NSD2KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL20538849 | 0.74 | KMT2A (0.78) | NSD2KMT2AHPGDKDM4EGAA | |
| SCHEMBL11941389 | 0.74 | NSD2 (0.61) | NSD2KMT2AHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068605-A1 | POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED BENZENES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-09-20 | — | — | WO | claimed |