Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14820895 | 0.92 | CTSK (0.57) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL7106483 | 0.88 | LMNA (0.60) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL14240829 | 0.87 | CTSK (0.48) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL15783776 | 0.87 | CTSK (0.48) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL15783777 | 0.87 | CTSK (0.48) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL5788596 | 0.87 | CNR1 (0.52) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL14808757 | 0.83 | CTSK (0.47) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL25497301 | 0.82 | CTSS (0.42) | CTSKCTSSGABRB1GABRB2PPARA | |
| SCHEMBL1786059 | 0.82 | LMNA (0.50) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL10530547 | 0.81 | CTSK (0.51) | CTSKCTSSMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |