Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483643 | 1.00 | TSHR (0.35) | TSHRHIF1AHSD17B10LMNANAAA | |
| SCHEMBL6397244 | 1.00 | TSHR (0.35) | TSHRHIF1AHSD17B10LMNANAAA | |
| SCHEMBL23148516 | 0.96 | L3MBTL1 (0.34) | TSHRHIF1AHSD17B10LMNAFFAR4 | |
| SCHEMBL1938964 | 0.89 | TSHR (0.35) | TSHRHIF1AHSD17B10LMNANAAA | |
| SCHEMBL7474587 | 0.86 | FFAR4 (0.30) | FFAR4 | |
| SCHEMBL9738855 | 0.84 | TSHR (0.45) | TSHRHSD17B10FFAR4ALDH1A1 | |
| SCHEMBL207971 | 0.83 | FFAR4 (0.35) | TSHRHIF1AHSD17B10LMNAFFAR4 | |
| SCHEMBL28432420 | 0.83 | ALDH1A1 (0.35) | TSHRHIF1AHSD17B10LMNAFFAR4 | |
| SCHEMBL15387457 | 0.82 | ALDH1A1 (0.34) | FFAR4ALDH1A1 | |
| SCHEMBL1938967 | 0.82 | NAAA (0.51) | TSHRNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | disclosed |
| EP-0309402-A1 | N-substituted hindered amine stabilizers | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |