Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 9/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465003 | 0.87 | HRH4 (0.54) | HRH4TSHRHSD17B10 | |
| SCHEMBL4310871 | 0.86 | MAPK1 (0.48) | HRH4TSHRHSD17B10NPC1RAB9A | |
| SCHEMBL4308039 | 0.83 | TSHR (0.48) | TSHRHSD17B10 | |
| SCHEMBL4324612 | 0.80 | HTR2C (0.48) | TSHRHSD17B10 | |
| SCHEMBL4326876 | 0.80 | HTR2C (0.48) | TSHRHSD17B10 | |
| SCHEMBL4315346 | 0.79 | CHRNB2 (0.46) | TSHRHSD17B10 | |
| SCHEMBL4312056 | 0.77 | MAPT (0.46) | TSHRHSD17B10 | |
| SCHEMBL4316201 | 0.76 | LTA4H (0.48) | HRH4TSHRHSD17B10 | |
| SCHEMBL7473246 | 0.76 | KDM1A (0.44) | HRH4 | |
| SCHEMBL4002342 | 0.75 | KDM4E (0.45) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178973-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000076984-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2000-12-21 | — | — | WO | disclosed |