Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480575 | 0.96 | MAPT (0.45) | MAPTPAOXALDH1A1TP53CYP3A4 | |
| SCHEMBL8198867 | 0.85 | DPP4 (0.39) | MAPTPAOXTP53CYP2C9CYP2C19 | |
| SCHEMBL7479744 | 0.84 | MAPT (0.50) | MAPTTP53BCHE | |
| SCHEMBL7480507 | 0.83 | MAPT (0.45) | MAPTALDH1A1TP53EPHX1GAA | |
| SCHEMBL27517935 | 0.75 | NPC1 (0.41) | MAPTTP53CYP2C9CYP2C19 | |
| SCHEMBL7474633 | 0.74 | MAPT (0.45) | MAPTPAOXALDH1A1CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL7472629 | 0.74 | MAPT (0.44) | MAPTPAOXALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7471137 | 0.74 | MEN1 (0.45) | MAPTTP53CYP2C9CYP2C19 | |
| SCHEMBL7480572 | 0.73 | PAOX (0.38) | MAPTPAOXALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7474634 | 0.72 | MAPT (0.49) | MAPTALDH1A1CYP3A4CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |