Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473656 | 0.83 | MAPT (0.45) | MAPTTP53ALDH1A1EPHX1GAA | |
| SCHEMBL7473837 | 0.82 | AKR1C3 (0.38) | HRH3KCNH2 | |
| SCHEMBL7479744 | 0.81 | MAPT (0.50) | MAPTTP53KMT2AMEN1HRH3 | |
| SCHEMBL7480575 | 0.81 | MAPT (0.45) | MAPTTP53ALDH1A1EPHX1GAA | |
| SCHEMBL27517935 | 0.80 | NPC1 (0.41) | MAPTTP53KMT2AMEN1 | |
| SCHEMBL7477516 | 0.79 | MAPT (0.45) | MAPTTP53ALDH1A1NPSR1KMT2A | |
| SCHEMBL7478289 | 0.74 | TP53 (0.47) | MAPTTP53ALDH1A1EPHX1GAA | |
| SCHEMBL25387621 | 0.70 | GLA (0.49) | ALDH1A1GAANPSR1KMT2AMEN1 | |
| SCHEMBL7979603 | 0.69 | ALDH1A1 (0.47) | ALDH1A1GAANPSR1KMT2AMEN1 | |
| SCHEMBL3231982 | 0.69 | GAA (0.50) | ALDH1A1GAANPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |