Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7472631 | 0.99 | MAPT (0.49) | MAPTALDH1A1EPHX1GAACYP3A4 | |
| SCHEMBL7484189 | 0.96 | MAPT (0.49) | MAPTALDH1A1EPHX1GAACYP2C9 | |
| SCHEMBL7471618 | 0.91 | KDM4E (0.45) | MAPTKDM4E | |
| SCHEMBL7479657 | 0.90 | MAPT (0.49) | MAPTALDH1A1EPHX1GAACYP2C9 | |
| SCHEMBL7473570 | 0.90 | MAPT (0.49) | MAPTALDH1A1EPHX1GAACYP2C9 | |
| SCHEMBL8175564 | 0.90 | L3MBTL1 (0.41) | MAPTGAAKDM4E | |
| SCHEMBL7484148 | 0.89 | KDM4E (0.50) | MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7483776 | 0.89 | MAPT (0.48) | MAPTALDH1A1EPHX1GAACYP2C9 | |
| Hydrochloric Acid SCHEMBL7480498 | 0.89 | MAPT (0.48) | MAPTALDH1A1EPHX1GAACYP2C9 | |
| SCHEMBL7479943 | 0.85 | GNAI3 (0.42) | MAPTCYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |