Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477702 | 0.89 | DNM1 (0.41) | HRH3POLBTSHRNPSR1 | |
| SCHEMBL7470756 | 0.80 | HRH3 (0.40) | HRH3LMNAKDM4EALDH1A1NPSR1 | |
| SCHEMBL7472666 | 0.80 | ACHE (0.40) | — | |
| Hydrochloric Acid SCHEMBL7478950 | 0.79 | ACHE (0.39) | — | |
| SCHEMBL7472660 | 0.79 | DPP4 (0.35) | NPSR1 | |
| SCHEMBL7473775 | 0.79 | DNM1 (0.37) | HRH3POLBTSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL7478947 | 0.78 | DPP4 (0.34) | GNAI3GNAO1GNAI1NPSR1 | |
| SCHEMBL7473778 | 0.78 | MEN1 (0.35) | — | |
| SCHEMBL7475264 | 0.77 | DNM1 (0.44) | NPSR1 | |
| SCHEMBL7481710 | 0.77 | MEN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |