SCHEMBL7475264

SCHEMBL7475264

CCCCCCCCCCCCCCCCCCNC(=O)N1CCCCC1CCOC(=O)CCCN(C)C

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.44
EPHX2 P34913 4/20 0.43
PRCP P42785 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
NAAA Q02083 1/20 0.36
DGKA P23743 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7472666 0.89 ACHE (0.40) DNM1
Hydrochloric Acid SCHEMBL7478950 0.88 ACHE (0.39) DNM1
SCHEMBL7467629 0.87 NPSR1 (0.36) DNM1NPSR1NAAA
SCHEMBL7480502 0.86 DNM1 (0.51) DNM1DGKA
SCHEMBL7477702 0.86 DNM1 (0.41) DNM1EPHX2NPSR1NAAA
SCHEMBL7481713 0.85 DNM1 (0.38) DNM1NPSR1
SCHEMBL7483673 0.84 MEN1 (0.43)
SCHEMBL7481061 0.83 NAAA (0.38) EPHX2NPSR1NAAA
SCHEMBL7474984 0.83 DNM1 (0.50) DNM1EPHX2NAAADGKA
SCHEMBL7472660 0.82 DPP4 (0.35) DNM1EPHX2NPSR1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933361-B1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO CO LTD (JP) 2002-03-27 EP disclosed
US-6057337-A USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS SHISEIDO CO., LTD. (JP) 2000-05-02 US disclosed
EP-0933361-A1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO COMPANY LIMITED (JP) 1999-08-04 EP disclosed