Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LRP6 | O75581 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891063 | 0.99 | LRP6 (0.33) | NPC1AVPR2HTR6MAPTSMN1; SMN2 | |
| SCHEMBL7483443 | 0.96 | LRP6 (0.34) | NPC1AVPR2MAPTSMN1; SMN2LRP6 | |
| SCHEMBL5650444 | 0.94 | MAPT (0.38) | NPC1MAPTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5645606 | 0.92 | MAPT (0.35) | MAPTSMN1; SMN2CYP2C9CYP2C19LRP6 | |
| SCHEMBL13868624 | 0.90 | KDM4E (0.35) | NPC1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14823294 | 0.89 | TP53 (0.35) | NPC1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7777302 | 0.88 | DHODH (0.37) | NPC1HTR6MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL13693075 | 0.88 | MAPT (0.37) | NPC1MAPTSMN1; SMN2CYP2C19MEN1 | |
| SCHEMBL5549293 | 0.88 | MAPT (0.39) | NPC1MAPTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL7488070 | 0.86 | ALDH1A1 (0.33) | NPC1MAPTSMN1; SMN2CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117656-B1 | GREY COLOURING PHOTOCHROMIC FUSED PYRANS | JAMES ROBINSON LTD (GB) | 2002-05-29 | — | — | EP | disclosed |
| US-6387512-B1 | FOR COLORING INKS, FUELS, PLASTICS OR GLASS | JAMES ROBINSON LIMITED (GB) | 2002-05-14 | — | — | US | disclosed |