Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRP6 | O75581 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891063 | 0.97 | LRP6 (0.33) | LRP6RAB9ASMN1; SMN2NPC1NPSR1 | |
| SCHEMBL5645606 | 0.96 | MAPT (0.35) | LRP6RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7473791 | 0.96 | NPC1 (0.33) | LRP6RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL13693075 | 0.92 | MAPT (0.37) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL5650444 | 0.90 | MAPT (0.38) | LRP6RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL7488070 | 0.88 | ALDH1A1 (0.33) | RAB9ASMN1; SMN2NPC1NPSR1KDM4E | |
| SCHEMBL5550993 | 0.87 | MAPT (0.38) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL14823294 | 0.87 | TP53 (0.35) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL7479868 | 0.86 | MEN1 (0.40) | RAB9ASMN1; SMN2NPC1KDM4EMAPT | |
| SCHEMBL7777302 | 0.85 | DHODH (0.37) | RAB9ASMN1; SMN2NPC1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117656-B1 | GREY COLOURING PHOTOCHROMIC FUSED PYRANS | JAMES ROBINSON LTD (GB) | 2002-05-29 | — | — | EP | disclosed |
| US-6387512-B1 | FOR COLORING INKS, FUELS, PLASTICS OR GLASS | JAMES ROBINSON LIMITED (GB) | 2002-05-14 | — | — | US | disclosed |