Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRP6 | O75581 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473791 | 0.99 | NPC1 (0.33) | LRP6NPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL7483443 | 0.97 | LRP6 (0.34) | LRP6NPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL5650444 | 0.94 | MAPT (0.38) | LRP6NPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL5645606 | 0.93 | MAPT (0.35) | LRP6MAPTSMN1; SMN2RAB9ACYP2C9 | |
| SCHEMBL14823294 | 0.90 | TP53 (0.35) | NPC1MAPTSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL7777302 | 0.89 | DHODH (0.37) | NPC1MAPTSMN1; SMN2RAB9AAHR | |
| SCHEMBL13868624 | 0.89 | KDM4E (0.35) | NPC1MAPTSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL13693075 | 0.89 | MAPT (0.37) | NPC1MAPTSMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL5549293 | 0.89 | MAPT (0.39) | NPC1MAPTSMN1; SMN2RAB9AAHR | |
| SCHEMBL14302089 | 0.87 | CNR2 (0.32) | NPC1MAPTSMN1; SMN2RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118702667-A | Photochromic dye compounds and their use in contact lenses for the correction of the red and green color blindness | 重庆蕾明视光科技有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-116836145-B | Polymerizable photochromic compound and application thereof | 重庆蕾明视光科技有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-116836145-A | Polymerizable photochromic compound and application thereof | 重庆蕾明视光科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
| US-11054558-B2 | Photochromic articles containing a porous material with a photochromic dye and fluid, methods of making and using | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-07-06 | — | — | US | disclosed |
| US-11054558-B2 | Photochromic articles containing a porous material with a photochromic dye and fluid, methods of making and using | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-07-06 | — | — | US | disclosed |
| US-20190324178-A1 | PHOTOCHROMIC ARTICLES CONTAINING A POROUS MATERIAL WITH A PHOTOCHROMIC DYE AND FLUID, METHODS OF MAKING AND USING | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-10-24 | — | — | US | disclosed |
| US-20190324178-A1 | PHOTOCHROMIC ARTICLES CONTAINING A POROUS MATERIAL WITH A PHOTOCHROMIC DYE AND FLUID, METHODS OF MAKING AND USING | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-10-24 | — | — | US | disclosed |
| US-8722076-B2 | Photochrome- or near IR dye-coupled polymeric matrices for medical articles | SURMODICS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-8722076-B2 | Photochrome- or near IR dye-coupled polymeric matrices for medical articles | SURMODICS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-8411347-B2 | Composition comprising photochromic dyes in an ionic solvent | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2013-04-02 | — | — | US | disclosed |
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | BANK OF MONTREAL, AS COLLATERAL AGENT | 2012-04-05 | — | — | US | disclosed |
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | BANK OF MONTREAL, AS COLLATERAL AGENT | 2012-04-05 | — | — | US | disclosed |
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | BANK OF MONTREAL, AS COLLATERAL AGENT | 2012-04-05 | — | — | US | disclosed |
| EP-1410784-B1 | Cosmetic composition comprising an oil phase and a naphthopyran dye and method | OREAL (FR) | 2007-02-07 | — | — | EP | disclosed |
| EP-1117656-B1 | GREY COLOURING PHOTOCHROMIC FUSED PYRANS | JAMES ROBINSON LTD (GB) | 2002-05-29 | — | — | EP | disclosed |
| US-6387512-B1 | FOR COLORING INKS, FUELS, PLASTICS OR GLASS | JAMES ROBINSON LIMITED (GB) | 2002-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | IK, PIR, PLOD1 | LRP6 543/4885NPC1 4846/4885MAPT 836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.