Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474658 | 0.96 | NPC1 (0.47) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL7479855 | 0.86 | NPC1 (0.44) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL7474618 | 0.85 | MEN1 (0.45) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL7478386 | 0.85 | GBA2 (0.41) | NPC1RAB9AHPGDMAPTTP53 | |
| SCHEMBL7483710 | 0.85 | GBA2 (0.41) | NPC1RAB9AHPGDMAPTTP53 | |
| SCHEMBL7480867 | 0.83 | NPSR1 (0.40) | MAPT | |
| SCHEMBL7479247 | 0.81 | MAPT (0.37) | MEN1KMT2AMAPTTP53CYP1A2 | |
| SCHEMBL9807017 | 0.80 | NPC1 (0.51) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL8178339 | 0.78 | MEN1 (0.53) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL7482491 | 0.78 | MEN1 (0.53) | NPC1RAB9AHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |