Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477702 | 0.87 | DNM1 (0.41) | NPSR1POLBTSHREPHX2HRH3 | |
| SCHEMBL7473874 | 0.83 | NPC1 (0.48) | MAPT | |
| SCHEMBL7478386 | 0.82 | GBA2 (0.41) | NPSR1EPHX2MAPT | |
| SCHEMBL7474658 | 0.82 | NPC1 (0.47) | MAPT | |
| SCHEMBL7483710 | 0.82 | GBA2 (0.41) | NPSR1EPHX2MAPT | |
| SCHEMBL7473013 | 0.80 | NAAA (0.47) | NPSR1EPHX2NAAAEPHX1 | |
| SCHEMBL7475772 | 0.80 | HRH3 (0.42) | POLBEPHX2HRH3MAPT | |
| SCHEMBL7479247 | 0.78 | MAPT (0.37) | MAPT | |
| SCHEMBL7481061 | 0.78 | NAAA (0.38) | NPSR1TSHREPHX2NAAAMAPT | |
| SCHEMBL7479943 | 0.78 | GNAI3 (0.42) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |