Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483710 | 0.98 | GBA2 (0.41) | GBA2MAPTTP53S1PR5S1PR1 | |
| SCHEMBL7482175 | 0.86 | GBA2 (0.40) | GBA2MAPTS1PR5S1PR1S1PR3 | |
| SCHEMBL7479285 | 0.86 | GBA2 (0.40) | GBA2MAPTS1PR5S1PR1S1PR3 | |
| SCHEMBL7473874 | 0.85 | NPC1 (0.48) | MAPTTP53NPC1HPGDRAB9A | |
| SCHEMBL7475380 | 0.84 | GBA2 (0.48) | GBA2MAPTS1PR5S1PR1S1PR3 | |
| SCHEMBL7474658 | 0.84 | NPC1 (0.47) | MAPTTP53NPC1HPGDRAB9A | |
| SCHEMBL7480867 | 0.82 | NPSR1 (0.40) | MAPTNPSR1EPHX2 | |
| SCHEMBL10612338 | 0.81 | GBA2 (0.53) | GBA2MAPTS1PR5S1PR1S1PR3 | |
| SCHEMBL9761016 | 0.80 | MAPT (0.43) | GBA2MAPTTP53S1PR5S1PR1 | |
| SCHEMBL7479247 | 0.80 | MAPT (0.37) | MAPTTP53S1PR5S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |