Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13077172 | 0.86 | NPC1 (0.50) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL9807026 | 0.84 | NPC1 (0.50) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL12522202 | 0.82 | ALDH1A1 (0.44) | NPC1RAB9AHPGDPOLB | |
| SCHEMBL9761016 | 0.82 | MAPT (0.43) | NPC1RAB9AMAPTTP53POLB | |
| SCHEMBL7473874 | 0.80 | NPC1 (0.48) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL9061218 | 0.79 | POLB (0.58) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL12522211 | 0.79 | ALDH1A1 (0.46) | NPC1RAB9APOLB | |
| SCHEMBL30484011 | 0.79 | POLB (0.58) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL7482491 | 0.79 | MEN1 (0.53) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL18533374 | 0.79 | NPC1 (0.46) | NPC1RAB9AHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281908-B1 | INSECT AND MITE REPELLENTS | BAYER AG (DE) | 1991-04-24 | — | — | EP | disclosed |
| US-4946850-A | APPLYING AN ACYLATED AMINO-ALCOHOL DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-08-07 | — | — | US | disclosed |
| US-4873252-A | Acylated aminoalcohols for repelling insects and mites | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-10 | — | — | US | disclosed |
| EP-0281908-A1 | Insect and mite repellents | BAYER AG (DE) | 1988-09-14 | — | — | EP | disclosed |