Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CBX7 | O95931 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961936 | 0.93 | PARP1 (0.34) | AVPR2AVPR1ACDK1CDK4CCND1 | |
| SCHEMBL7972159 | 0.86 | AVPR2 (0.34) | AVPR2AVPR1ACDK1CDK4CCND1 | |
| SCHEMBL7966823 | 0.86 | AVPR2 (0.34) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7478475 | 0.85 | CBX7 (0.38) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7968982 | 0.85 | AVPR2 (0.33) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7486482 | 0.84 | RAB9A (0.35) | AVPR2AVPR1ACDK1CDK4CCND1 | |
| SCHEMBL7596846 | 0.84 | AVPR2 (0.33) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7781332 | 0.83 | KMT2A (0.39) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7476401 | 0.83 | MEN1 (0.35) | AVPR2AVPR1ACDK1CDK4CCND1 | |
| Hydrochloric Acid SCHEMBL7967336 | 0.83 | AVPR2 (0.33) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |